This book illustrates the main results deriving from fourteen studies, dealing with the impact of climate change on different agricultural and natural ecosystems, carried out within the Impact of Climate change On agricultural and Natural Ecosystems (ICONE) project funded by the ALFA Programme of the European Commission. During this project, a common methodology on several Global Change-related matters was developed and shared among members of scientific communities coming from Latin America and Europe. In order to facilitate this interdisciplinary approach, specific mobility programmes, addressed to post-graduate, Master and PhD students, have been organized. The research, led by the research groups, was focused on the study of the impact of climate change on various environmental features (i.e. runoff in hydrological basins, soil erosion and moisture, forest canopy, sugarcane crop, land use, drought, precipitation, etc). Integrated and shared methodologies of atmospheric physics, remote sensing, eco-physiology and modelling have been applied.